Single cell analysis is an emerging technology that helps sequence whole human genome at a single cell level. This particularly includes genomics, transcriptomics, proteomics, epigenomics, and metabolomics with its sensitivity improved to single cell level. In genomics, new generation methodologies such as next generation sequencing and third generation sequencing play crucial roles. The aim of single cell analysis is mainly to measure and analyze cellular heterogeneity. Single cell analysis interpret life at fundamental level and find immense applications in the field of medicine. Single cell analysis over conventional standard cell numbers sequencing method enable the discovery and investigation of unknown micro-organisms. A study published in the Journal of Single Cell Analysis 2014, stated that a variety of technologies that are powerful and less expensive, such as Multiple Annealing And Looping-Based Amplification Cycle (MALBAC) and Multiple Displacement Amplification (MDA), find great progress in uncovering somatic mutations in human genome and detection of copy number variation. But in human single-cell genomics, Whole Genome Sequencing or Whole Exome-Sequencing (WGS or WESseq) finds great potential in clinical applications, especially in screening, diagnosis, and monitoring. It is popular in academic research because mRNA helps bridge genome structure and epigenomics modification with phenotype, reveals gene functions and regulatory network, and most importantly it is easier to perform than proteomics.
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Major Company Profiles Covered in This Report: 10X Genomics, Abcam Plc., Agilent Technologies, Fluxion Biosciences, Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, Bruker, Danaher Corporation, Fluidigm Corporation, GE Healthcare, and Illumina, among others.
Inclination toward single-cell technology by biologists is mainly because many samples including stem cells, immune cells, neurons, cancers, and other tissues exhibit a stochastic nature with heterogeneity factor. Conventional methods cannot provide transcriptomic profile in highly heterogeneous cell population. Even if cell population is less, single cell analysis can enable the identification of biomarkers of delicate phenotypes or disorders (e.g. cancer stem cells). In addition, this analytical technique also helps classify different cell types in different physiological and pathological conditions, in very rare events of any somatic mutation, epigenetic modification of regulatory gene expression, and its function.
10x Genomics, in 2017, launched the chromium single cell V(D)J solution for profiling full length paired V(D)J transcripts from hundreds to millions of lymphocyte. It is a reagent system, which has the ability to completely identify and characterize T and B cells by single cell sequencing. This will reveal true clonality and diversity in adaptive immune system. This product will have an impact on research based single cell analysis market.
Adoption rate of treatment options, for instance, stem cell therapy and in-vitro fertilization (IVF) is increasing significantly. Moreover, long shelf life of single cell analysis products and consumable products is another driver for the growth of single cell analysis market.
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Table of Content
Global Single Cell Analysis Market Research Report
Section 1: Global Single Cell Analysis Industry Overview
Section 2: Global Economic Impact on Single Cell Analysis Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Single Cell Analysis Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy, and Downstream Buyers
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